Renal Dysplasia

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Renal dysplasia may be unilateral or bilateral. Animals affected bilaterally generally die in the early neonatal period, whereas animals affected unilaterally typically develop hypertrophy of the contralateral kidney. The kidneys are usually small, firm, and pale; they may have a uniformly diminished renal cortex. Histologic examination reveals immature glomeruli, primitive tubules, and secondary inflammatory lesions, especially interstitial fibrous connective tissue.

Renal dysplasia is a disorder in which the kidneys do not develop normally. It most commonly affects Shih Tzus, Lhasa apsos, and soft-coated wheaten terriers. Dogs usually become clinically ill before 1 year of age.Unfortunately, this genetic disease has no cure; many affected dogs will develop kidney failure. Management options are limited and generally expensive.

Although some dogs are only carriers of this disorder and have normal kidney function, they can still pass the trait onto their offspring. If you’re a breeder, testing for renal dysplasia can significantly reduce your chances of breeding this inherited problem in your dogs. Please call us to schedule this test.

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